Bipolar Research

News and Articles

Upcoming Events

Save the Date for NAMIWALK SF Bay Area!  Saturday, May 22, 2010, again in San Francisco's Golden Gate Park.  The Bipolar Disorder Research Program will be walking -- team name: All For Balance. If you would like to support All For Balance, or walk with us, click on


Bipolar Research Program:  In the News

Trisha Suppes, M.D., Ph.D. receives the 2008 Gerald L. Klerman Senior Investigator Award

Medscape Interview with Director Trisha Suppes, M.D., Ph.D.


Recent Publications

Altshular LL, Kupka RW, Hellemann G, Frye MA, Sugar CA, McElroy SL, Nolen WA, Grunze H, Leverich GS, Keck PE Jr, Zermeno M, Post RM, Suppes T.  Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network.  American Journal of Psychiatry, in press. Epub: March 15, 2010.

Ivleva, EI, Morris DW, Moates AF, Suppes T, Thaker GK, Tamminga CA.  Genetics and intermediate phenotypes of the schizophrenia-bipolar boundary. Neuroscience and Biobehavioral Reviews, 2010; 34(6): 897-921. Epub: November 30, 2009; doi: 10.1016/j.neubiorev.2009.11.022.

Suppes T, Datto C, Minkwitz M, Nordenhem A, Walker C, Darko D. Effectiveness of the extended-release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression (Trial D144CC00002), Journal of Affective Disorders, 2010; 121: 106-115. Epub: November 8, 2009; doi: 10.1016/j.jad.2009.10.007.

Goldberg JF, Calabrese JR, Saville BR, Frye MA, Ketter TA, Suppes T, Post RM, Goodwin FK. Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo. Journal of Clinical Psychiatry, 2009. Epub: August 11, 2009; doi: 10.4088/JCP.08m04381.

Bernstein IH, Rush AJ, Suppes T, Trivedi MH, Woo A, Yasushi K, Crismon ML, Dennehy E, Carmody TJ (2009). A psychometric evaluation of the clinician-rated Quick Inventory of Depressive Symptomatology (Qids-C16) in bipolar patients. International Journal of Methods in Psychiatric Research, 2009; 18(2): 138-146. Epub: Nov 29, 2008; doi: 10.1002/mpr.285.

Tohen M, Frank E, Bowden CL, Colom F, Ghaemi NS, Yatham LN, Malhi GS, Calabrese JR, Nolen WA, Vieta E, Kapczinski F, Goodwin GM, Suppes T, Sachs GS, Chengappa KNR, Grunze H, Mitchell PB, Kanba S, Berk M.  The International Society of Bipolar Disorders (ISBD) Task Force on the nomenclature of course and outcome in bipolar disorders. Bipolar Disorders, 2009; 11(5): 453-473. doi: 10.1111/j.1399-5618.2009.00726.x.

Dennehy EB, Schnyer R, Bernstein IH, Gonzalez R, Shivakumar G, Kelly DI, Snow DE, Sureddi S, Suppes T. The safety, acceptability, and effectiveness of acupuncture as an adjunctive treatment for bipolar disorder. Journal of Clinical Psychiatry, 2009; 70(6): 897-905. Epub: May 5, 2009; doi:10.4088/JCP.08m04208.

Altshuler L, Post RM, Hellemann G, Leverich GS, Nolen W, Frye M, Keck PE Jr, Kupka R, Grunze H, Elroy SL, Sugar C, Suppes T.  Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: A blinded, randomized study. Journal of Clinical Psychiatry, 2009; 70(4): 450-7. Epub: April 7, 2009; doi: 10.4088/JCP.08m04191.

Suppes T, Vieta E, Liu S, Brecher M, Paulsson B. Maintenance Treatment for Patients with Bipolar I Disorder: Results from a North American study of quetiapine in combination with lithium or divalproex (Trial 127). American Journal of Psychiatry, 2009; 166(4): 476-88. Epub: Mar 16, 2009; doi: 10.1176/appi.ajp.2008.08020189.

Frye MA, Yatham L, Ketter TA, Goldberg J, Suppes T, Calabrese JR, Bowden CL, Bourne E, Bahn R, Adam B. Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies. Acta Psychiatrica Scandinavica, 2009; 120(1): 10-3. Epub: Jan 31, 2009; doi: 10.1111/j.1600-0447.2008.01343.x.

Sheehan DV, McElroy SL, Harnett-Sheehan K, Keck PE Jr., Janavs J, Rogers J, Gonzalez R, Shivakumar G, Suppes T. Randomized, Placebo-controlled trial of risperidone for acute treatment of bipolar anxiety. Journal of Affective Disorders, 2009; 115(3): 376-85. Epub: November 29, 2008; doi: 10.1016/j.jad.2008.10.005.



Suppes T, Dennehy E. Bipolar Disorder: The Latest Diagnostic and Treatment Strategy, Compact Clinicals, 2005.

Suppes T, Manning JS, Keck PE Jr. Decoding Bipolar Disorder, Compact Clinicals, 2006.

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